脱发有什么成因？

1. 荷尔蒙失衡：掉发的隐形元凶

DHT 与雄性秃（Androgenetic Alopecia）

二氢睾酮（DHT）是睾固酮的衍生物，当 DHT 与头皮毛囊受体结合时，会导致毛囊萎缩，进而引发男性或女性型秃发。即使是女性，也会因雌激素代谢产生 DHT，因此维持荷尔蒙平衡对预防脱发至关重要。

怀孕与产后掉发

怀孕期间，雌激素水平升高可延长头发的生长期，但产后雌激素骤降，可能导致大量脱发。此外，月经周期与更年期的荷尔蒙变化也可能加速脱发。

甲状腺功能不平衡

甲状腺功能过低（甲状腺低能）会影响新陈代谢，导致毛囊功能受损，使头发变得干燥、脆弱；而甲状腺功能过高致新陈代谢过快，则可能引发过度脱发。

长期压力与皮质醇（Cortisol）

压力会提高皮质醇水平，这种分解代谢型荷尔蒙会破坏身体组织，包括毛囊，进而干扰生长周期，导致发量减少。

2. 营养缺乏：头发健康的关键

铁质缺乏与头发生长

经期过多或铁质吸收不良可能导致贫血，铁质是形成血红蛋白的主要成分，血红蛋白把氧气及营养输送至身体不同细胞包括头发细胞，缺乏铁质影响毛囊氧气及营养供应，导致脱发。

维生素 B 群与肠道健康

生物素（Biotin）与维生素 B 群的不足，常与肠道问题（如胀气、消化不良）有关。肠道菌群的健康如同「土壤」，能促进毛囊这些「根部」的生长。保护肠道微生物菌健康很重要，因为肠道微生物会产生氨基酸，令头发生长。肠道微生物群被破坏可导致头皮微生物破坏，进而导致头皮屑、脱发及皮肤病等问题。

如何治疗脱发？个性化方案打造健康发质

第一步：全方位健康检测

通过荷尔蒙检测（DHT、皮质醇、甲状腺素）与营养评估（铁质、维生素 B 群），找出脱发的根本原因。此外，头皮分析可帮助评估毛囊健康，进一步制定专属疗程。

第二步：个性化的脱发治疗方案

荷尔蒙疗法

• 针对 DHT 过高者：可使用 DHT 阻断剂（如非那雄胺 Finasteride），但需监测副作用（如性欲降低）。年长男性可搭配睾固酮补充，以维持活力。

• 针对雌激素或甲状腺失衡者：可通过荷尔蒙替代疗法（HRT）或甲状腺药物来调整平衡。

营养补充与饮食调整

针对营养缺乏者：可使用高品质的医学级补充品，并通过饮食计划来改善营养状况。若肠道吸收不佳，可考虑营养静脉注射或益生菌疗程来提升吸收效率。

生活方式调整

压力管理：冥想、运动等方式可降低皮质醇的影响，减少压力引起的掉发。头皮保养：头皮按摩可促进血液循环，有助于毛囊健康。

第三步：先进的再生医学疗法

外泌体疗法（Exosome Therapy）

外泌体是由干细胞释放的微小囊泡，其中含有生长因子与胜肽，可直接传递至头皮，修复毛囊、刺激生长并延长头发生长周期。与传统干细胞疗法不同，外泌体是细胞间的「讯号」，可精准调控细胞修复机制，提供长效且针对性的脱发治疗效果。 这种微创技术已成为头发再生领域的突破性疗法。

为什么选择整体健康策略治疗脱发？

脱发 不仅仅是美观问题，它更反映身体的内在健康。通过个性化治疗，结合荷尔蒙调节、营养补充与再生医学技术（如外泌体疗法），能有效解决脱发问题。建议寻求专业医疗机构，通过整合医学与再生疗法，为您制定专属的生发计划。

了解你的内在健康，结合现代科学技术，从内以外解决您的脱发问题，重新长出浓密秀发，让你找回自信，迎向美好的未来！

准备重拾浓密秀发？立即预约免费头皮分析

如果您有脱发烦恼及想寻求有关生发方案， 欢迎联系我们， 预约免费头皮分析与咨询，或了解更多疗程资讯。

关于LifeClinic： 香港 头发再生专家

Lifeclinic 是一间位于香港中环区的抗衰老医疗中心，在生发领域拥有超过 15 年的经验。我们致力于提供医学级的全方位头发再生疗程，确保患者获得最佳效果。我们遵循国际标准，严格执行医疗操作程序，包括无菌处理与专业技术，为每位患者提供最安全、有效的治疗方案。 立即联络我们，开启您的健康生发之旅！

参考资料:

Ellis, J. A., Sinclair, R., & Harrap, S. B. (2002). Androgenetic alopecia: Pathogenesis and potential for therapy. Expert Reviews in Molecular Medicine, 4(22), 1-11.  

Kaufman, K. D. (2002). Clinical studies on the effects of finasteride on hair growth in men. Journal of the American Academy of Dermatology, 46(6), 818-826.  

Rushton, D. H., Ramsay, I. D., James, K. C., & Norris, M. J. (2002). Biochemical and trichological characterization of diffuse alopecia in women. British Journal of Dermatology, 147(1), 41-47.  

Trost, L. B., Bergfeld, W. F., & Calogeras, E. (2006). The diagnosis and treatment of iron deficiency and its potential relationship to hair loss. Journal of the American Academy of Dermatology, 54(5), 824-844.  

Patel, D. P., Swink, S. M., & Castelo-Soccio, L. (2017). A review of the use of biotin for hair loss. Skin Appendage Disorders, 3(3), 166-169.  

Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P., & Tosti, A. (2019). The role of vitamins and minerals in hair loss: A review. Dermatology and Therapy, 9(1), 51-70.  

Rajendran, R. L., Girija, A. R., Balasubramanian, S., et al. (2022). Stem cell-derived exosomes: A nano platform for therapeutics and drug delivery in combating alopecia. Life Sciences, 289, 120210.  

其他关于脱发的文章:

Functional Remedies of Hair Loss

男性掉发的功能性原因

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Rates of melanoma, the deadliest form of skin cancer, has been rising for at least the last three decades, and this increase has been largely blamed on the exposure to (UV) light from the sun.

(Source: British Journal of Dermatology)

Rates of melanoma, the deadliest form of skin cancer, has been rising for at least the last three decades, and this increase has been largely blamed on the exposure to (UV) light from the sun.

However a recent study published in the British Journal of Dermatology revealed that an epidemic of the disease has broken out among indoor workers. These workers get three to nine times LESS solar UV exposure than outdoor workers get, yet only the indoor workers have increasing rates of melanoma — and the rates have been increasing since before 1940.

There are two major factors that help explain this, and the first has to do with the type of UV exposure.

There are two primary types of UV rays from sunlight, the vitamin-D-producing UVB rays and the skin-damaging UVA light. Both UVA and UVB can cause tanning and burning, although UVB does so far more rapidly. UVA, however, penetrates your skin more deeply than UVB, and may be a much more important factor in photo-aging, wrinkles and skin cancers.

A study in Medical Hypotheses suggested that indoor workers may have increased rates of melanoma because they’re exposed to sunlight through windows, and only UVA light, unlike UVB, can pass through window glass. At the same time, these indoor workers are missing out on exposure to the beneficial UVB rays, and have lower levels of vitamin D.

Researchers wrote:
“We hypothesize that one factor involves indoor exposures to UVA (321–400nm) passing through windows, which can cause mutations and can break down vitamin D3 formed after outdoor UVB (290–320nm) exposure, and the other factor involves low levels of cutaneous vitamin D3. After vitamin D3 forms, melanoma cells can convert it to the hormone, 1,25-dihydroxyvitamin D3, or calcitriol, which causes growth inhibition and apoptotic cell death in vitro and in vivo. … We agree that intense, intermittent outdoor UV overexposures and sunburns initiate CMM [cutaneous malignant melanoma]; we now propose that increased UVA exposures and inadequately maintained cutaneous levels of vitamin D3 promotes CMM.”

To put it simply, UVB appears to be protective against melanoma — or rather, the vitamin D your body produces in response to UVB radiation is protective.
As written in The Lancet (vol 363, issue 9410, pp 728-730):

“Paradoxically, outdoor workers have a decreased risk of melanoma compared with indoor workers, suggesting that chronic sunlight exposure can have a protective effect.”

Your organs can convert the vitamin D in your bloodstream into calcitriol, which is the hormonal or activated version of vitamin D. Your organs then use it to repair damage, including damage from cancer cells and tumors. Vitamin D’s protective effect against cancer works in multiple ways, including:

• Increasing the self-destruction of mutated cells (which, if allowed to replicate, could lead to cancer)
• Reducing the spread and reproduction of cancer cells
• Causing cells to become differentiated (cancer cells often lack differentiation)
• Reducing the growth of new blood vessels from pre-existing ones, which is a step in the transition of dormant tumors turning cancerous

This applies not only to skin cancer but other types of cancer as well. Theories linking vitamin D to certain cancers have been tested and confirmed in more than 200 epidemiological studies, and understanding of its physiological basis stems from more than 2,500 laboratory studies, according to epidemiologist Cedric Garland, DrPH, professor of family and preventive medicine at the UC San Diego School of Medicine.

LifeClinic Says:

LifeClinic recommends using the sun therapeutically, this means getting the proper exposure to optimize your vitamin D levels. This typically means exposing enough of your unclothed skin surface to get a slight pink color on your skin. Your exact time will vary radically depending on many variables, such as you skin color, time of day, season, clouds, altitude and age.

The key principle is to never get burned, while still spending as much time as you can in the sun during the peak hours, as it is virtually impossible to overdose as long as you don’t get burned.

The best time to be in the sun for vitamin D production is actually as near to solar noon as possible which is 1 PM in the summer for most (due to Daylight Saving Time). The more damaging UVA rays are quite constant during ALL hours of daylight, throughout the entire year — unlike UVB, which are low in morning and evening and high at midday.

Most people with fair skin will max out their vitamin D production in just 10-20 minutes, or, again, when your skin starts turning the lightest shade of pink. Some will need less, others more. The darker your skin, the longer exposure you will need to optimize your vitamin D production.

If you work in an office, or get limited opportunities to go into the sun at peak hours, we recommend you have your Vitamin D levels checked, which can be done on a simple blood test. If they are low, they can be easily supplemented with a daily vitamin D3 capsule.

Optimizing your levels of Vitamin D3 may not only just protect against malignant melanoma, but has also been shown to reduce the risk of getting cancer of the colon, prostate, breast and lymphoma.

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