{"id":6350,"date":"2020-05-15T17:55:38","date_gmt":"2020-05-15T09:55:38","guid":{"rendered":"http:\/\/lifeclinic.com.hk\/cytokine-therapy-101-2\/"},"modified":"2025-04-14T10:19:31","modified_gmt":"2025-04-14T02:19:31","slug":"nad-therapy-101","status":"publish","type":"post","link":"https:\/\/lifeclinic.com.hk\/nad-therapy-101\/","title":{"rendered":"NAD+ Therapy 101"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><span style=\"font-size: 14pt;\"><strong><em>Nicotinamide adenine dinucleotide (NAD+):<\/em> a critical coenzyme found in every cell in your body and involved in hundreds of metabolic processes.<\/strong><\/span><\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_81 counter-hierarchy ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title ez-toc-toggle\" style=\"cursor:pointer\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/lifeclinic.com.hk\/nad-therapy-101\/#What_is_NAD\" >What is NAD+?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/lifeclinic.com.hk\/nad-therapy-101\/#How_does_NAD_Therapy_help\" >How does NAD+ Therapy help?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/lifeclinic.com.hk\/nad-therapy-101\/#NAD_Mechanisms\" >NAD+ Mechanisms:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/lifeclinic.com.hk\/nad-therapy-101\/#What_People_are_Saying\" >What People are Saying?<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_is_NAD\"><\/span><strong><u><span style=\"font-size: 18pt;\">What is NAD+?<\/span> <\/u><\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Nicotinamide adenine dinucleotide (NAD+) is a naturally occurring coenzyme found in virtually every cell. Its function is to help catalyse reactions in the body and is heavily involved in cell regeneration, DNA repair, cell metabolism and the production of cellular energy.\u00a0Unfortunately, this invaluable compound rapidly declines with age<sup>1<\/sup>.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_does_NAD_Therapy_help\"><\/span><span style=\"font-size: 18pt;\"><strong><u>How does NAD+ Therapy help?<\/u><\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Emerging evidence suggests that higher NAD+ levels may slow or even reverse aspects of aging and age-related diseases, including obesity, diabetes, cardiovascular diseases and neurodegenerative conditions<sup>2<\/sup>. This is because as NAD+ levels drop, the pathways that NAD+ operate become compromised leading to accelerated aging and a greater risk for developing a range of diseases. Numerous clinical trials have been published on NAD+ Therapy and it is typically very well-tolerated<sup>5<\/sup>. Side effects are rare and usually mild, such as flushing.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"NAD_Mechanisms\"><\/span><span style=\"font-size: 18pt;\"><strong><u>NAD+ Mechanisms:<\/u><\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ol>\n<li>May contribute to longer telomeres for anti-aging<\/li>\n<li>Promotes DNA repair<\/li>\n<li>Modulates immune-cell signaling<\/li>\n<li>Improves mental clarity, focus and concentration<\/li>\n<li>Boosts mood<\/li>\n<li>Mitigates chemical stress inflammation<\/li>\n<li>Activates sirtuins<sup>3<\/sup><\/li>\n<li>Supports energy production<sup>4<\/sup><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_People_are_Saying\"><\/span><span style=\"font-size: 18pt;\"><strong><u>What People are Saying?<\/u><\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>\u201cFountain of youth molecule\u201d &#8211; Dr. David Sinclair, Ph.D, Professor in Department of Genetics, Harvard Medical School<\/p>\n<p>&nbsp;<\/p>\n<p>\u201cPotentially one of the greatest advances in medical science since the invention of penicillin.\u201d- Dr. Phillip Milgram, Scripps Memorial Hospital<\/p>\n<p>&nbsp;<\/p>\n<p>&#8220;The next big anti-aging drug&#8221; &#8211; Dr. Ross Grant, Australasian Research Institute<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><u>References<\/u><\/p>\n<ol>\n<li>Schultz MB, Sinclair DA. Why NAD(+) Declines during Aging: It&#8217;s Destroyed.\u00a0<em>Cell Metab<\/em>. 2016;23(6):965\u2010 doi:10.1016\/j.cmet.2016.05.022<\/li>\n<li>Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes<\/li>\n<li>Blander G, Guarente L (2004). &#8220;The Sir2 family of protein deacetylases.&#8221; Annu. Rev. Biochem. 73: 417\u201335.<\/li>\n<li>B\u00fcrkle A (2005). &#8220;Poly(ADP-ribose). The most elaborate metabolite of NAD+.&#8221; FEBS J. 272 (18): 4576\u201389.<\/li>\n<li>Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults<\/li>\n<\/ol>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"Nicotinamide adenine dinucleotide (NAD+): a critical coenzyme found in every cell in your body and involved in hundreds of metabolic processes. What is NAD+? Nicotinamide adenine dinucleotide (NAD+) is a naturally occurring coenzyme found in virtually every cell. Its function is to help catalyse reactions in the body and is heavily involved in cell regeneration, [...]","protected":false},"author":4,"featured_media":6352,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[252,202,206],"tags":[],"class_list":["post-6350","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anti-aging","category-biohacking","category-brain-cognition"],"acf":[],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2020\/05\/nad.jpg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/6350","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/comments?post=6350"}],"version-history":[{"count":4,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/6350\/revisions"}],"predecessor-version":[{"id":8862,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/6350\/revisions\/8862"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/media\/6352"}],"wp:attachment":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/media?parent=6350"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/categories?post=6350"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/tags?post=6350"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}