{"id":7007,"date":"2021-10-20T03:10:33","date_gmt":"2021-10-19T19:10:33","guid":{"rendered":"http:\/\/lifeclinic.com.hk\/the-impacts-of-stress-on-hormones-2\/"},"modified":"2025-04-14T11:58:05","modified_gmt":"2025-04-14T03:58:05","slug":"demystifying-the-metabolic-system","status":"publish","type":"post","link":"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/","title":{"rendered":"Demystifying the Metabolic System"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>A slow metabolism is sometimes blamed for a wide range of complaints \u2013 weight gain, fatigue, dull skin and more. But what really is \u201cmetabolism\u201d, how is it measured, and how can we optimize it?<\/p>\n<p>Your body is an incredible machine that is able to take the energy from the food we eat, and transform it into energy our cells can use. Simply put, the combined reactions that make up this process is our metabolic system, also termed metabolism. Our metabolism is <em>not<\/em> just how fast or how slow we burn calories (aka our metabolic rate).<\/p>\n<p>At a high level, we can break our metabolic system into two overriding categories: the breakdown of energy and nutrients (catabolism), and the building of tissues and energy stores (anabolism). The breakdown of food during digestion would be a catabolic reaction, while the storage of fuel in the form of fat would be an anabolic reaction. Our body is in a constant flux between these states depending on a wide range of factors like our nutrient status, the time of day, what we\u2019re doing at the moment, hormone balance etc.<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div  class=\"wpb_single_image wpb_content_element vc_align_left wpb_content_element\">\n\t\t\n\t\t<figure class=\"wpb_wrapper vc_figure\">\n\t\t\t<div class=\"vc_single_image-wrapper   vc_box_border_grey\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"255\" src=\"https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/10\/pathways.jpeg\" class=\"vc_single_image-img attachment-full\" alt=\"\" title=\"pathways\" srcset=\"https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/10\/pathways.jpeg 800w, https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/10\/pathways-300x96.jpeg 300w, https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/10\/pathways-768x245.jpeg 768w, https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/10\/pathways-18x6.jpeg 18w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/div>\n\t\t<\/figure>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>There are thousands of reactions involved in our metabolism; from breaking down the energy from food to converting that energy to fuel for our cells, and finally, clearing out waste products. Three of the most important pathways for energy production are glycolysis, the citric acid cycle, and the electron transport chain. Together, these pathways take glucose from our food to create energy in the form of ATP molecules. These small but mighty molecules of ATP then go on to power virtually everything we do: from making new cells to tissue repair to brainpower to movement!<\/p>\n<p>Having a strong metabolic system, or what scientists call &#8216;metabolic integrity&#8217;, is truly at the foundation of feeling, looking, and performing our best. When metabolic integrity is seriously and\/or chronically compromised, metabolic syndrome can occur with the telltale symptoms of increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels. But aside from clinical conditions, what are indicators that our metabolism is working optimally?<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_81 counter-hierarchy ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title ez-toc-toggle\" style=\"cursor:pointer\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/#Indicators_of_Metabolic_Integrity\" >Indicators of Metabolic Integrity:<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/#Healthy_Digestion\" >Healthy Digestion<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/#High_Mitochondrial_Function\" >High Mitochondrial Function<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/#Balanced_Blood_Sugar_Levels\" >Balanced Blood Sugar Levels<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/#Balanced_Hormone_Levels\" >Balanced Hormone Levels<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/#Balanced_Neurotransmitter_Levels\" >Balanced Neurotransmitter Levels<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/lifeclinic.com.hk\/demystifying-the-metabolic-system\/#Proper_Excretion_of_Waste\" >Proper Excretion of Waste<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Indicators_of_Metabolic_Integrity\"><\/span><span style=\"font-size: 18pt;\">Indicators of Metabolic Integrity:<\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li>\n<h3><span class=\"ez-toc-section\" id=\"Healthy_Digestion\"><\/span><u><span style=\"font-size: 14pt;\">Healthy Digestion<\/span> <\/u><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<\/li>\n<\/ul>\n<p>Metabolism starts with the breakdown and extraction of energy and nutrients from food. A well-oiled digestive process will ensure that those nutrients (such as glucose, which we know is the substrate for glycolysis) are feeding our metabolic pathways for energy.<\/p>\n<ul>\n<li>\n<h3><span class=\"ez-toc-section\" id=\"High_Mitochondrial_Function\"><\/span><span style=\"font-size: 14pt;\"><u>High Mitochondrial Function<\/u><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<\/li>\n<\/ul>\n<p>Our mitochondria are termed the \u201cenergy powerhouses of the cell\u201d, and for good reason. So many key processes like the citric acid cycle and the electron transport chain rely on the machinery of the mitochondria. If these intracellular organelles are not working optimally, then the energy from our food won\u2019t be efficiently converted into energy that we can use.<\/p>\n<ul>\n<li>\n<h3><span class=\"ez-toc-section\" id=\"Balanced_Blood_Sugar_Levels\"><\/span><span style=\"font-size: 14pt;\"><u>Balanced Blood Sugar Levels<\/u><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<\/li>\n<\/ul>\n<p>Our body carefully tracks how much glucose is available and regulates blood sugar accordingly. Higher glucose (such as after eating) will be metabolised and stored, while lower glucose (such as fasting or after exercise) stimulates our cells to tap into our stores. As glucose is so key to our metabolic pathways, our blood sugar balance is essential for maintaining a healthy metabolic system.<\/p>\n<ul>\n<li>\n<h3><span class=\"ez-toc-section\" id=\"Balanced_Hormone_Levels\"><\/span><span style=\"font-size: 14pt;\"><u>Balanced Hormone Levels<\/u><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<\/li>\n<\/ul>\n<p>Hormones like insulin, estrogen, testosterone and growth hormone are the signals to when we should store energy (and where and how) as well as when we should break down our stores and shuttle those nutrients into our metabolic pathways. Dysregulation can occur due to many internal factors as well as our lifestyle habits.<\/p>\n<ul>\n<li>\n<h3><span class=\"ez-toc-section\" id=\"Balanced_Neurotransmitter_Levels\"><\/span><span style=\"font-size: 14pt;\"><u>Balanced Neurotransmitter Levels<\/u><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<\/li>\n<\/ul>\n<p>Neurotransmitters also provide signals that direct our metabolic processes. Unlike hormones, neurotransmitters can have faster but short-lived effects. Epinephrine and norepinephrine act as neurotransmitters that regulate the body&#8217;s \u201cfight or flight\u201d response. This involves preparing the body with the energy it may need in response to stressors.<\/p>\n<ul>\n<li>\n<h3><span class=\"ez-toc-section\" id=\"Proper_Excretion_of_Waste\"><\/span><span style=\"font-size: 14pt;\"><u>Proper Excretion of Waste<\/u><\/span><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<\/li>\n<\/ul>\n<p>Our metabolic pathways supply our cells with the nutrients and energy they need. However, these pathways will often create waste products that our body has no use of and must excrete in a safe and timely manner. Metabolic waste products include carbon dioxide (CO2), urea, and ammonia. Backlogs in excretion processes can leave us feeling very poorly, and over time can severely damage our excretion organs and overall health.<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>It might seem like a lot can go wrong and sabotage your metabolic system. In a way, that\u2019s true, but our everyday lifestyle choices affect each and every one of these indications. Therefore, we have a remarkable ability to optimize our metabolic pathways, and a responsibility to keep it working in top condition.<\/p>\n<p>In Functional Medicine, there are many indicators of sub-optimal metabolic health. Some of these may present as noticeable symptoms like fatigue, unexpected changes in weight, hair loss, frequently feeling cold, dry skin, low mood, headaches, and brain fog. However, laboratory testing is essential to checking your metabolic health as well as helping to pinpoint the specific pathways that can be optimized. The best test to assess metabolic integrity is an <strong>Organic Acids Test (OAT)<\/strong>. With a simple urine sample, this test analyses chemical by-products of key metabolic reactions. With this data, we have a snapshot into how smoothly your chemical pathways are working and how to optimize your metabolism.<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/lifeclinic.com.hk\/contact-us\/\">Contact us<\/a> to learn more about your metabolism and how to support your body to achieve your life goals.<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div><div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>References:<\/p>\n<ol>\n<li>Angione C. Human Systems Biology and Metabolic Modelling: A Review-From Disease Metabolism to Precision Medicine.\u00a0<em>Biomed Res Int<\/em>. 2019;2019:8304260. Published 2019 Jun 9. doi:10.1155\/2019\/8304260<\/li>\n<li>Dunn WB, Ellis DI. Metabolomics: current analytical platforms and methodologies.\u00a0<em>TrAC Trends Anal Chem.<\/em>\u00a0(2005) 24:285\u201394. doi: 10.1016\/j.trac.2004.11.021<\/li>\n<li>Lau DC, Yan H, Dhillon B. Metabolic syndrome: a marker of patients at high cardiovascular risk.\u00a0<em>Can J Cardiol<\/em>. 2006;22 Suppl B(Suppl B):85B-90B. doi:10.1016\/s0828-282x(06)70992-8<\/li>\n<li>Rochlani Y, Pothineni NV, Kovelamudi S, Mehta JL. Metabolic syndrome: pathophysiology, management, and modulation by natural compounds.\u00a0<em>Ther Adv Cardiovasc Dis<\/em>. 2017;11(8):215-225. doi:10.1177\/1753944717711379<\/li>\n<li>Tsoukalas D, Alegakis A, Fragkiadaki P, et al. Application of metabolomics: Focus on the quantification of organic acids in healthy adults.\u00a0<em>Int J Mol Med<\/em>. 2017;40(1):112-120. doi:10.3892\/ijmm.2017.2983<\/li>\n<\/ol>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"A slow metabolism is sometimes blamed for a wide range of complaints \u2013 weight gain, fatigue, dull skin and more. But what really is \u201cmetabolism\u201d, how is it measured, and how can we optimize it? Your body is an incredible machine that is able to take the energy from the food we eat, and transform [...]","protected":false},"author":4,"featured_media":7010,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[202,204],"tags":[],"class_list":["post-7007","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biohacking","category-functional-medicine"],"acf":[],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/10\/metabolism2.jpeg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/7007","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/comments?post=7007"}],"version-history":[{"count":5,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/7007\/revisions"}],"predecessor-version":[{"id":8888,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/7007\/revisions\/8888"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/media\/7010"}],"wp:attachment":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/media?parent=7007"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/categories?post=7007"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/tags?post=7007"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}