{"id":7220,"date":"2021-11-21T12:28:43","date_gmt":"2021-11-21T04:28:43","guid":{"rendered":"http:\/\/lifeclinic.com.hk\/diving-into-gut-inflammation-2\/"},"modified":"2025-04-14T11:52:18","modified_gmt":"2025-04-14T03:52:18","slug":"how-nad-works-to-biohack-energy","status":"publish","type":"post","link":"https:\/\/lifeclinic.com.hk\/how-nad-works-to-biohack-energy\/","title":{"rendered":"How NAD+ Works to Biohack Energy"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>Low energy, fatigue, feeling <em>meh<\/em>, constant drowsiness, a lack of motivation, burn out, etc. is one of the top complaints of modern-day city dwellers. This leads many of us to wonder, \u201cHow much more could I achieve if I was able to tap into my full energy potential?\u201d Scientists around the world are looking into a possible answer, and it\u2019s in the form of one tiny molecule with huge potential \u2013 NAD+.<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_81 counter-hierarchy ez-toc-counter ez-toc-light-blue ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title ez-toc-toggle\" style=\"cursor:pointer\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/lifeclinic.com.hk\/how-nad-works-to-biohack-energy\/#What_is_NAD\" >What is NAD+?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/lifeclinic.com.hk\/how-nad-works-to-biohack-energy\/#How_is_it_used_for_energy\" >How is it used for energy?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/lifeclinic.com.hk\/how-nad-works-to-biohack-energy\/#How_can_I_improve_my_NAD_status\" >How can I improve my NAD+ status?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/lifeclinic.com.hk\/how-nad-works-to-biohack-energy\/#What_other_benefits_does_NAD_have_on_the_body\" >What other benefits does NAD+ have on the body?<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"What_is_NAD\"><\/span><span style=\"font-size: 18pt;\"><strong>What is NAD+?<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor in all living cells. In other words, it is a small molecule needed for larger chemical reactions to occur. Many of these key reactions are related to energy production within the mitochondria of our cells.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_is_it_used_for_energy\"><\/span><span style=\"font-size: 18pt;\"><strong>How is it used for energy?<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>NAD+ comes in two forms: NAD+ and NADH, which are called the oxidized and reduced forms, respectively. These forms are constantly interchanging. For NAD+ to become NADH it gains a charged hydrogen molecule (H+) and 2 electrons. You can imagine NAD+ as an empty car driving around the body and NADH as a full car looking to drop off its passengers so they can join other teams and get to work. The shuttling of these electron passengers is critical for energy metabolism, or the conversion of our food into energy our cells can utilize.<\/p>\n<p>Thinking back to high-school biology, the food you eat goes through three phases to become energy: glycolysis, the Krebs Cycle, and the electron transport chain. During glycolysis and the Krebs Cycle, NAD+ is converted into NADH molecules. These NADH molecules then go on to the electron transport chain (in the mitochondria) to give up their electrons to create a large amount of energy in the form of ATP (adenosine triphosphate) \u2014 the energy currency of the cell.<\/p>\n<p>Without NAD+\/NADH shuttling electrons through this complex metabolic system, we simply wouldn\u2019t be getting our ATP payoff for the food we eat.<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div  class=\"wpb_single_image wpb_content_element vc_align_left wpb_content_element\">\n\t\t\n\t\t<figure class=\"wpb_wrapper vc_figure\">\n\t\t\t<div class=\"vc_single_image-wrapper   vc_box_border_grey\"><img loading=\"lazy\" decoding=\"async\" width=\"1280\" height=\"720\" src=\"https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/11\/electon-transport-chain.jpeg\" class=\"vc_single_image-img attachment-full\" alt=\"\" title=\"electon transport chain\" srcset=\"https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/11\/electon-transport-chain.jpeg 1280w, https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/11\/electon-transport-chain-300x169.jpeg 300w, https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/11\/electon-transport-chain-1024x576.jpeg 1024w, https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/11\/electon-transport-chain-768x432.jpeg 768w, https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/11\/electon-transport-chain-18x10.jpeg 18w\" sizes=\"auto, (max-width: 1280px) 100vw, 1280px\" \/><\/div>\n\t\t<\/figure>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h2><span class=\"ez-toc-section\" id=\"How_can_I_improve_my_NAD_status\"><\/span><span style=\"font-size: 18pt;\"><strong>How can I improve my NAD+ status?<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>NAD+ is made internally and is actually found in a large number of species including mammals, yeast, bacteria and even plants. However, as we age, our NAD+ levels drop substantially. Scientists estimate that NAD+ falls to half that of youthful levels at 40 years old and by 80, it is down to 1%-10%.<\/p>\n<p>Alleviating this natural decline in NAD+ levels has huge potential for drastically slowing down, and even reversing, the signs of aging. Supporting NAD+ levels helps protect the mitochondria from damage and keeps mitochondrial function high. When you keep the mitochondria happy, you help ensure that your cells are receiving the energy it needs to function optimally, making you feel a whole lot better!<\/p>\n<p>NAD+ can be taken orally, through high-quality supplementation schemes, intramuscularly or intravenously. Intravenous NAD+ allows it to bypass the stomach for greater effects on the body. Intravenous NAD+ is also able to be transported directly to the brain to help mental fatigue, brain fog, memory, motivation and cognition.<\/p>\n<p>Numerous clinical trials have been published on NAD+ Therapy and it is typically very well-tolerated. Side effects are typically mild, such as flushing, and would be monitored by the medical professional administering the therapy.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_other_benefits_does_NAD_have_on_the_body\"><\/span><span style=\"font-size: 18pt;\"><strong>What other benefits does NAD+ have on the body?<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>In addition to energy, maintaining healthy levels of NAD+ is also important for:<\/p>\n<ul>\n<li>Promoting longevity<\/li>\n<li>Reducing external signs of aging like wrinkles<\/li>\n<li>Protecting memory and cognition<\/li>\n<li>Supporting positive mood balance<\/li>\n<li>Fighting off cardiovascular disease<\/li>\n<li>Supporting chromosome stability (involved in cancer risk)<\/li>\n<\/ul>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div>\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><a href=\"https:\/\/lifeclinic.com.hk\/contact-us\/\">Contact us<\/a> to learn more about how to support your NAD+ levels for improved energy.<\/p>\n\n\t\t<\/div>\n\t<\/div>\n<div class=\"vc_empty_space\"   style=\"height: 32px\"><span class=\"vc_empty_space_inner\"><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p>References:<\/p>\n<ol>\n<li style=\"list-style-type: none;\">\n<ol>\n<li>Braidy N, Berg J, Clement J, et al. Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes.\u00a0<em>Antioxid Redox Signal<\/em>. 2019;30(2):251-294. doi:10.1089\/ars.2017.7269<\/li>\n<li>Cant\u00f3 C, Menzies KJ, Auwerx J. NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.\u00a0<em>Cell Metab<\/em>. 2015;22(1):31-53. doi:10.1016\/j.cmet.2015.05.023<\/li>\n<li>Chini CCS, Tarrag\u00f3 MG, Chini EN. NAD and the aging process: Role in life, death and everything in between.\u00a0<em>Mol Cell Endocrinol<\/em>. 2017;455:62-74. doi:10.1016\/j.mce.2016.11.003<\/li>\n<li>Dietrich C, Charles B, Claire LK. \u201cSafety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults.\u201d <em>Sci Rep<\/em>. 2019 Jul 5;9(1):9772. doi: 10.1038\/s41598-019-46120-z.<\/li>\n<li>Verdin E. NAD\u207a in aging, metabolism, and neurodegeneration.\u00a0<em>Science<\/em>. 2015;350(6265):1208-1213. doi:10.1126\/science.aac4854<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><div class=\"vc_row wpb_row vc_row-fluid\"><div class=\"wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner\"><div class=\"wpb_wrapper\"><\/div><\/div><\/div><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"Low energy, fatigue, feeling meh, constant drowsiness, a lack of motivation, burn out, etc. is one of the top complaints of modern-day city dwellers. This leads many of us to wonder, \u201cHow much more could I achieve if I was able to tap into my full energy potential?\u201d Scientists around the world are looking into [...]","protected":false},"author":4,"featured_media":7224,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[202,204],"tags":[],"class_list":["post-7220","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biohacking","category-functional-medicine"],"acf":[],"aioseo_notices":[],"jetpack_featured_media_url":"https:\/\/lifeclinic.com.hk\/wp-content\/uploads\/2021\/11\/nad.jpeg","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/7220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/comments?post=7220"}],"version-history":[{"count":4,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/7220\/revisions"}],"predecessor-version":[{"id":8884,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/posts\/7220\/revisions\/8884"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/media\/7224"}],"wp:attachment":[{"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/media?parent=7220"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/categories?post=7220"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeclinic.com.hk\/wp-json\/wp\/v2\/tags?post=7220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}